Cosmetic products are an important element in human society. The use of cosmetics has implications of health hazards; hence, modern cosmetic technology is in search of naturally-derived cosmetics. In this chapter, cosmetics derived from synthetic polymers, polysaccharide-based polymers, protein, and silicone-based materials are discussed Particularly, synthetic polymers have changed the personal care industry dramatically by increased the use of favorable synthetic polymers that are soluble in various organic solvents like methyl chloride, ethyl alcohol, iso-propanol, toluene, and so forth. This route is environment-friendly